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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRLF1
All Species:
14.55
Human Site:
S636
Identified Species:
45.71
UniProt:
Q9NRY4
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRY4
NP_004482.4
1513
172229
S636
D
G
K
M
Y
E
L
S
L
R
P
I
E
G
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112719
1499
170555
S636
D
G
K
M
Y
E
L
S
L
R
P
I
E
G
N
Dog
Lupus familis
XP_850368
1503
172366
D633
D
G
K
I
Y
E
L
D
L
R
P
V
D
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91YM2
1499
170374
S636
D
G
K
M
Y
E
L
S
L
R
P
I
E
G
N
Rat
Rattus norvegicus
P81128
1513
172361
S636
D
G
K
M
Y
E
L
S
L
R
P
I
E
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510691
1429
157109
G614
E
I
R
A
L
C
T
G
D
D
Q
F
V
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX32
1561
178754
I618
D
L
L
N
D
I
R
I
C
T
G
S
K
G
E
Honey Bee
Apis mellifera
XP_624122
1551
176949
T589
A
R
E
I
R
A
Q
T
E
D
D
E
V
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.4
50.7
N.A.
96.5
94.5
N.A.
64.9
N.A.
N.A.
N.A.
N.A.
27.9
29
N.A.
N.A.
Protein Similarity:
100
N.A.
98.6
69.3
N.A.
97.6
96.3
N.A.
78.2
N.A.
N.A.
N.A.
N.A.
49.2
48.8
N.A.
N.A.
P-Site Identity:
100
N.A.
100
60
N.A.
100
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
100
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
13
0
13
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% C
% Asp:
75
0
0
0
13
0
0
13
13
25
13
0
13
0
0
% D
% Glu:
13
0
13
0
0
63
0
0
13
0
0
13
50
13
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% F
% Gly:
0
63
0
0
0
0
0
13
0
0
13
0
0
63
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
25
0
13
0
13
0
0
0
50
0
0
13
% I
% Lys:
0
0
63
0
0
0
0
0
0
0
0
0
13
0
13
% K
% Leu:
0
13
13
0
13
0
63
0
63
0
0
0
0
0
0
% L
% Met:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% Q
% Arg:
0
13
13
0
13
0
13
0
0
63
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
13
0
0
0
% S
% Thr:
0
0
0
0
0
0
13
13
0
13
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
13
25
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
63
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _